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Department of Natural Sciences 

RESEARCH DATA BASE

Sherrice Allen, Ph.D.

 

Assistant Professor of Biology

 

Office Location: LS 309
Phone: (910) 672-1046
Fax: (910) 672-1159
Research Website: ?

Email: svallen@uncfsu.edu

Research Interests:

The focus of my research is to provide genetic and biochemical evidence for a de novo folic acid pathway in Pseudomonas aeruginosa, PAO1 as well as identifying biochemical pathways in the in the rice blast fungus, Magnaporthe grisea that may have putative roles in infection and pathogenesis.  By using genetic biochemical analysis we are attempting to establish the existence of key enzymes in the de novo folic acid pathway that are genetically and biochemically similar to their E. coli homologs that may serve as a target for novel antimicrobial agents.  Research with the rice blast fungus Magnaporthe grisea, relies on using genetic disruption of key genes shown to be unregulated during infection and may have a roles in regulating early events of the host-pathogen recognition process, including the induction of a specialized infection cell, the appressorium as well as during a full blown infection.

Grants and Awards:

 

Selected Publications:  

1)Timothy R. Dean, Sherrice V. Allen, and Eric Miller, "In vitro Selection of Phage RB69 RegA RNA Binding Sites Yields UAA Repeats", Virology 336 (2005), 26-36 

2) Allen,Sherrice,"Earning a Ph.D. in Microbiology quot;, Minority Scientists Network, Science Nextwave (web article), American Association for the Advancement of Science, May 2002. (http:nextwave.science.org/miscinet).

3) Sherrice V. Allen and Eric S. Miller, "RNA-Binding Properties of in vitro Expressed Histidine-Tagged RB69 RegA Translational Repressor Protein", Anal Biochem 269, 32-37